pentobarbital will decrease the level or outcome of ethotoin by affecting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Watch.pentobarbital will minimize the extent or outcome of tramadol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. Reduced AUC of tramadol as well as the active metabolite (O-desmethyltrama… Read More